Abstract:

In this study the potentialities of quantitative computed tomography (QCT) in bone densitometry is reported. QCT was performed in patients receiving glucocorticoid therapy and in postmenopausal women (55 patients all in all). Special software was used for the mineral density loss assessment: surrounding tissues were automatically subtracted, and calculating of the vertebral body density done in cross-sectional view. QCT allows specifying pathological changes in any vertebral structures and so serves as a good contribution to the diagnosis of osteoporosis. 

Reference

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Abstract:

Aim: was to determine the level of bilateral asymmetry of mineral density of trabecular and cortical bones in lumbar spine in women as an additional diagnostic criterion for osteoporosis, using quantitative computed tomography

Material and methods: the study included 210 women, postmenopausal, who underwent bone densitometry by quantitative computed tomography Estimated total body BMD II-IV of the lumbar vertebrae (separately for trabecular and cortical bone), as well as bilateral asymmetry indices BMD - BMD ratio of the largest one-half of the vertebral BMD to the other half.

Results: with increasing age of the surveyed, noted the growth of bilateral asymmetry index values mineral density of the lumbar vertebrae for both trabecular and cortical bones. Decrease in bone mass of the lumbar vertebrae is associated with an increase in bilateral asymmetry of the BMD. The correlation between the BMD and bilateral asymmetry indices for trabecular bone was r = -0.52 (p=0.001) for cortical bone r = - 0.47 (p=0.001).

Conclusion: the index of bilateral asymmetry in bone mineral density of the vertebral bodies car serve as an additional diagnostic criterion for osteoporosis during bone densitometry by quantitative computed tomography in postmenopausal women.

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11.  Zaharov I